Carbohydrate synthesis from lactate in pigeon-liver homogenate

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Carbohydrate synthesis from lactate in pigeon-liver homogenate.

Andrews, P. (1962). Nature, Lond., 196, 36. Bjork, I. (1960). Biochim. biophy8. Acta, 45, 372. Blumberg, B. S. & Ogston, A. G. (1956). Biochem. J. 63, 715. Dische, Z. (1947). J. biol. Chem. 167, 189. Dittebrandt, M. (1948). Amer. J. clin. Path. 18, 439. Dreywood, R. (1946). Indu8tr. Engng Chem. (Anal.), 18, 499. Johnston, J. P. (1955). Biochem. J. 59, 620. Laurent, T. C. (1963 a). Biochem. J. 8...

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Effects of 4-pentenoic acid on carbohydrate metabolism in pigeon liver homogenate.

The addition of 4-pentenoic acid to liver homogenates results in a decrease in long chain fatty acids oxidation and in gluconeogenesis. Glycolysis is not affected, whereas lactate oxidation to CO2 is inhibited. There is an increased formation of alanine and decreased levels of glutamate and aspartate. The inhibition of gluconeogenesis is partially reversed by the addition of short chain fatty a...

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Carbohydrate Metabolism in Pigeon -Liver Homogenates

1. The effects of added AMP on carbohydrate metabolism were investigated in pigeon-liver homogenates, which can degrade glucose and synthesize it from lactate. Suitable experimental conditions were established for studying such effects, including the addition of P1 (20mM) to stabilize adenine nucleotides and supplementation with NAD+ (0.5mM). 2. Lactate increased the rate of oxygen consumption ...

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Fatty acid synthesis from acetate by human liver homogenate fractions.

Evidence obtained during the last few years has shown that fatty acid synthesis in a variety of mammalian tissues (1-4) as well as in yeast (5, 6) and bacteria (7, 8) is not simply the reverse of fatty acid oxidation. This is borne out by the finding that oxidative processes seem to be confined to the mitochondrial portion of the cell, whereas fatty acid synthesis apparently occurs in extramito...

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The regulation of phosphoenolpyruvate synthesis in pigeon liver.

1. The intracellular location and maximal activities of enzymes involved in phosphoenolpyruvate synthesis have been investigated in pigeon liver. Enolase and pyruvate kinase were cytoplasmic, and the activities were 50-60 and 180-210mumoles/min./g. dry wt. at 25 degrees respectively. Phosphoenolpyruvate carboxykinase was present exclusively, and nucleoside diphosphokinase predominantly, in the ...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1964

ISSN: 0006-2936

DOI: 10.1042/bj0930112